Wound Repair Regen. View abstract. Water Res 2010;44(14):4105-4114. Chun, J. Y., Kang, H. K., Jeong, L., Kang, Y. O., Oh, J. E., Yeo, I. S., Jung, S. Y., Park, W. H., and Min, B. M. Epidermal cellular response to poly(vinyl alcohol) nanofibers containing silver nanoparticles. Meyer, J. N., Lord, C. A., Yang, X. Y., Turner, E. A., Badireddy, A. R., Marinakos, S. M., Chilkoti, A., Wiesner, M. R., and Auffan, M. Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans. ChemMedChem. Demir, E., Vales, G., Kaya, B., Creus, A., and Marcos, R. Genotoxic analysis of silver nanoparticles in Drosophila. Proceedings of the 17th Conference of the European Wound Management Association. Wiegand, C., Heinze, T., and Hipler, U. C. Comparative in vitro study on cytotoxicity, antimicrobial activity, and binding capacity for pathophysiological factors in chronic wounds of alginate and silver-containing alginate. Gou, N., Onnis-Hayden, A., and Gu, A. Shrivastava, S., Singh, S. K., Mukhopadhyay, A., Sinha, A. S., Mandal, R. K., and Dash, D. Negative regulation of fibrin polymerization and clot formation by nanoparticles of silver. A study of the Gram-negative bacterium Escherichia coli. Lohsiriwat, V. and Chuangsuwanich, A. The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion. Sondi, I. and Salopek-Sondi, B. J Colloid Interface Sci 11-1-2007;315(1):389-395. View abstract. Kheng, D. Evaluation of Mepilex Ag, a silver impregnated soft silicone absorbent dressing in patients with critically colonized venous leg ulcers - 5 case reviews. Taylor R. Nanosafety and the environment.
Sathishkumar, M., Sneha, K., Won, S. W., Cho, C. W., Kim, S., and Yun, Y. S. Cinnamon zeylanicum bark extract and powder mediated green synthesis of nano-crystalline silver particles and its bactericidal activity. Cohen LE, Spurlock R, Salem A, Mercado E. Argyria in the silver state. Gulbranson SH, Hud JA, Hansen RC. 12-18-2009;390(3):733-737. Cutis 2000;66:373-4. I. Toxicol.Lett 9-15-1998;98(3):169-179. 2008;28(2):97-99. Hyun, J. S., Lee, B. S., Ryu, H. Y., Sung, J. H., Chung, K. H., and Yu, I. J. Neurotoxicol.Teratol. Pariser, R. J. Generalized argyria. Colloids Surf.B Biointerfaces. 2010;38(12):2246-2251. In fact, the FDA deemed that all over-the-counter products that contain colloidal silver ingredients or silver salts are not generally recognized as safe or effective (1, 2). Silver deposits may also occur in your intestines, liver, kidneys, and other organs (14). The future is now: wound care in the 21st century. J Biomed.Mater.Res B Appl Biomater. View abstract. Childress, B. 2-24-2009;3(2):279-290. Kim, Y. S., Kim, J. S., Cho, H. S., Rha, D. S., Kim, J. M., Park, J. D., Choi, B. S., Lim, R., Chang, H. K., Chung, Y. H., Kwon, I. H., Jeong, J., Han, B. S., and Yu, I. J. Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats. Kemp, M. M., Kumar, A., Clement, D., Ajayan, P., Mousa, S., and Linhardt, R. J. Hyaluronan- and heparin-reduced silver nanoparticles with antimicrobial properties. Ecotoxicology. 10-15-2010;100(2):140-150. Wong, K. K., Cheung, S. O., Huang, L., Niu, J., Tao, C., Ho, C. M., Che, C. M., and Tam, P. K. Further evidence of the anti-inflammatory effects of silver nanoparticles. View abstract. Appl Microbiol.Biotechnol. Int Wound J 2010;7(4):262-270. View abstract. View abstract. View abstract. Li, W. R., Xie, X. Environ Sci Technol. Water Res 2010;44(20):6095-6103. Biochem.Biophys.Res Commun. 11-12-2009;18(20):S28, S30-S28, S36. View abstract. View abstract. Int J Nanomedicine. View abstract. Interact.Cardiovasc.Thorac.Surg 2009;8(1):153-154. Toxicol.Sci 2009;107(2):404-415. View abstract. Colloidal silver is commonly found as a dietary supplement in liquid or spray form. Jun, E. A., Lim, K. M., Kim, K., Bae, O. N., Noh, J. Y., Chung, K. H., and Chung, J. H. Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity. Ahamed, M., Posgai, R., Gorey, T. J., Nielsen, M., Hussain, S. M., and Rowe, J. J. Colloidal silver products were once available as over-the-counter drug products. Muller, G. and Kramer, A. Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity. Zhang, B., Luo, Y., and Wang, Q. Colloids Surf.B Biointerfaces. van, Hasselt P., Gashe, B. View abstract. View abstract.
Can J Ophthalmol. View abstract. J Burn Care Rehabil 1998;19(6):531-537.
5-15-2009;43(10):3933-3940. Wu, M. H. and Wu, H. Y. Silver resistance in MRSA isolated from wound and nasal sources in humans and animals. 2007; Silva, L. R., Gurgel, R. Q., Lima, D. R., and Cuevas, L. E. Current usefulness of Crede's method of preventing neonatal ophthalmia. 2010;5(4):044103. Toxicol.Sci 2010;115(2):521-534. Ophthalmology 1991;98(12):1769-1775. Selective inhibitory potential of silver nanoparticles on the harmful cyanobacterium Microcystis aeruginosa. View abstract. J Med Assoc.Thai. J Phys Chem.B 10-30-2008;112(43):13608-13619. Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos. View abstract. 2010;8:19. Small 8-17-2009;5(16):1897-1910. 11-1-2010;44(21):8337-8342. Its proponents claim that it treats various diseases, such as cancer, HIV, Lyme disease, and diabetes. J Nanobiotechnology. Wunderlich, U. and Orfanos, C. E. [Treatment of venous ulcera cruris with dry wound dressings. View abstract. Biological effects induced by nanosilver particles: in vivo study. 6-23-2009;3(6):1357-1364. 1960;63:586-591. Bong-Hyun, J, Jang-Woong, B, and Jee Yeon, K et al. You are encouraged to report negative side effects of prescription drugs to the FDA. Its present in very tiny amounts in drinking water, the food supply, and even the air you breathe (8). View abstract. Gopinath, P., Gogoi, S. K., Sanpui, P., Paul, A., Chattopadhyay, A., and Ghosh, S. S. Signaling gene cascade in silver nanoparticle induced apoptosis. Influence of hydrocolloidal silver nanoparticles on gastrointestinal microflora and morphology of enterocytes of quails. 2-25-2009;20(8):085103. Chen, X. and Schluesener, H. J. Nanosilver: a nanoproduct in medical application. View abstract. Kumari, M., Mukherjee, A., and Chandrasekaran, N. Genotoxicity of silver nanoparticles in Allium cepa. 8-15-2010;142(1-2):222-228. Hua Xi.Kou Qiang.Yi.Xue.Za Zhi. View abstract. Biotechnol.Lett 2008;30(11):1893-1899. J Biomed.Opt. Safety evaluation of silver nanoparticles: inhalation model for chronic exposure. B. Antibacterial activity and mechanism of silver nanoparticles on Escherichia coli. J Air Waste Manag.Assoc. View abstract. 3-15-2010;44(6):2163-2168. View abstract. Colloidal silvers mechanisms arent fully understood. View abstract. Biomaterials 2010;31(8):2260-2271. Gerding, R. L., Emerman, C. L., Effron, D., Lukens, T., Imbembo, A. L., and Fratianne, R. B. Outpatient management of partial-thickness burns: Biobrane versus 1% silver sulfadiazine. J Mater.Sci Mater.Med 2010;21(10):2861-2868. Romanko, M. I., Rieznichenko, L. S., Hruzina, T. H., Dybkova, S. M., Ul'berh, Z. R., Ushkalov, V. O., and Holovko, A. M. [Influence of gold and silver nanoparticles on ATPase activity of native and rehydrated cells of Escherichia coli]. View abstract. Shouse, S. S. and Whipple, G. H. I. What Is Japanese Knotweed, and Should You Try It. Environ Health Perspect. ACS Nano. View abstract. Choi, O. and Hu, Z. Numerous case studies have found that silver intake from colloidal silver dietary supplements may lead to argyria (15, 16, 17). (7). Colloidal silver might decrease how much tetracycline antibiotics the body can absorb. In fact, its considered unsafe and ineffective by the FDA. Trickler, W. J., Lantz, S. M., Murdock, R. C., Schrand, A. M., Robinson, B. L., Newport, G. D., Schlager, J. J., Oldenburg, S. J., Paule, M. G., Slikker, W., Jr., Hussain, S. M., and Ali, S. F. Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells. Silver bullet. Muhling, M., Bradford, A., Readman, J. W., Somerfield, P. J., and Handy, R. D. An investigation into the effects of silver nanoparticles on antibiotic resistance of naturally occurring bacteria in an estuarine sediment. Akhavan, O. Sudheer, Khan S., Bharath, Kumar E., Mukherjee, A., and Chandrasekaran, N. Bacterial tolerance to silver nanoparticles (SNPs): Aeromonas punctata isolated from sewage environment. 2010;84(1):63-69. 1993; Hwang, E. T., Lee, J. H., Chae, Y. J., Kim, Y. S., Kim, B. C., Sang, B. I., and Gu, M. B.
Parker, W. A. Argyria and cyanotic heart disease. 2010;5:337-342. Storm-Versloot, M. N., Vos, C. G., Ubbink, D. T., and Vermeulen, H. Topical silver for preventing wound infection. Supplement Safety. View abstract. 2010;398(2):867-876.
Morones, J. R., Elechiguerra, J. L., Camacho, A., Holt, K., Kouri, J. Int Wound J 2005;2(4):348-356. View abstract. 2010;6(2):192-197. In fact, the earliest recorded use of silver as a medical treatment dates back to the Han Dynasty in China (1500 B.C.) A Comparison of Three Silver-containing Dressings in the Treatment of Infected, Chronic Wounds. View abstract. Rev Latinoam.Microbiol. There are many Internet ads for the parts of a generator that produces colloidal silver at home. Environ Toxicol.Chem. Development of a New Polypropylene-Based Suture: Plasma Grafting, Surface Treatment, Characterization, and Biocompatibility Studies. Aquat.Toxicol. Elliott, C. The effects of silver dressings on chronic and burns wound healing. Rapid repair and regeneration of damaged rabbit sciatic nerves by tissue-engineered scaffold made from nano-silver and collagen type I. This can lead to an irreversible bluish skin discoloration that first appears in the gums. Role of sulfide and ligand strength in controlling nanosilver toxicity. Taking colloidal silver along with medications that might also harm the liver can increase the risk of liver damage. View abstract. Powers, C. M., Badireddy, A. R., Ryde, I. T., Seidler, F. J., and Slotkin, T. A. J Basic Microbiol. 6-1-2010;77(2):240-245. The effect of silver nanoparticles on phytopathogenic spores of Fusarium culmorum. Evaluation of the toxic impact of silver nanoparticles on Japanese medaka (Oryzias latipes). J Biol Inorg.Chem. View abstract. Colloidal silver proteins marketed as health supplements. Studies on interaction of colloidal Ag nanoparticles with Bovine Serum Albumin (BSA). Nanotechnology. Biotechnol.Bioeng.
View abstract. Proliferation and survival of rat C6 glioma culture in the presence of implants coated with modified carbon-based films. View abstract. View abstract. Jin, X., Li, M., Wang, J., Marambio-Jones, C., Peng, F., Huang, X., Damoiseaux, R., and Hoek, E. M. High-throughput screening of silver nanoparticle stability and bacterial inactivation in aquatic media: influence of specific ions. Better Nutrition 2010;72(11):8. 12-1-2010;81(2):555-562. View abstract. Hussain, S. M. and Schlager, J. J. Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes. Foldbjerg, R., Olesen, P., Hougaard, M., Dang, D. A., Hoffmann, H. J., and Autrup, H. PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes. Li, Q., Mahendra, S., Lyon, D. Y., Brunet, L., Liga, M. V., Li, D., and Alvarez, P. J. Antimicrobial nanomaterials for water disinfection and microbial control: potential applications and implications. Br J Surg 2001;88(1):4-21. De, Gusseme B., Sintubin, L., Baert, L., Thibo, E., Hennebel, T., Vermeulen, G., Uyttendaele, M., Verstraete, W., and Boon, N. Biogenic silver for disinfection of water contaminated with viruses. View abstract. Vijayakumar, P. S. and Prasad, B. L. Intracellular biogenic silver nanoparticles for the generation of carbon supported antiviral and sustained bactericidal agents. View abstract. View abstract. View abstract. 11-11-2009;20(45):455104. View abstract. Liu, Z., Ren, G., Zhang, T., and Yang, Z. View abstract. View abstract. Clinicopathologic features and histochemical studies. View abstract. Macromol.Biosci. In fact, the FDA considers colloidal silver unsafe for human intake due to its harmful effects and buildup in the organs. View abstract. View abstract. [Effect of silver preparations on the microflora regenerated from a condensate of atmospheric water vapor in a hermetically-sealed chamber]. Biotechnol.Adv. Apt, L., Isenberg, S. J., and Yoshimori, R. Antimicrobial preparation of the eye for surgery.
View abstract. View abstract. View abstract. Silver products for medical indications: risk-benefit assessment. J Burn Care Res 2006;27(3):298-309. Tian, J., Wong, K. K., Ho, C. M., Lok, C. N., Yu, W. Y., Che, C. M., Chiu, J. F., and Tam, P. K. Topical delivery of silver nanoparticles promotes wound healing. Mohammed, Fayaz A., Balaji, K., Girilal, M., Kalaichelvan, P. T., and Venkatesan, R. Mycobased synthesis of silver nanoparticles and their incorporation into sodium alginate films for vegetable and fruit preservation. Further, no human data supports consuming colloidal silver to treat or prevent medical conditions like diabetes, cancer, HIV, digestive issues, and other illnesses (8). A. and Caldwell, D. R. Corneal argyrosis: histologic, ultrastructural and microanalytic study. Lo, S. F., Hayter, M., Chang, C. J., Hu, W. Y., and Lee, L. L. A systematic review of silver-releasing dressings in the management of infected chronic wounds. Finally, silver is found in other commercial products, such as cleaning agents, agricultural treatments, and personal hygiene products like shower gels and deodorants (7). 2007;12(4):527-534. Honey compared with 1% silver sulfadiazine cream in the treatment of superficial and partial thickness burns. The real risks of ingesting silver nanoparticles, which are present in colloidal silver products, are also unknown. Despite these concerns about safety and effectiveness, people still buy colloidal silver as a dietary supplement and use it for a wide range of ailments. Sadhasivam, S., Shanmugam, P., and Yun, K. Biosynthesis of silver nanoparticles by Streptomyces hygroscopicus and antimicrobial activity against medically important pathogenic microorganisms. J Control Release 7-14-2010;145(2):76-90. Mol.Pharm 2009;6(5):1388-1401. Am J Clin Dermatol 2010;11(1):35-44.
9-18-2009;138(3-4):325-329. 2009;5(4):452-456. Cai, Y. H. and Lu, C. S. [A clinical study of gelatamp colloidal silver gelatin sponge on preventing the complication of teeth extraction]. 10-28-2005;(40):5059-5061. Graefes Arch Clin Exp.Ophthalmol.
View abstract. Biometals 2011;24(1):135-141. View abstract. Alt, V., Bechert, T., Steinrucke, P., Wagener, M., Seidel, P., Dingeldein, E., Scheddin, D., Domann, E., and Schnettler, R. [Nanoparticulate silver. Fung MC, Weintraub M, Bowen DL. Choi, O., Yu, C. P., Esteban, Fernandez G., and Hu, Z. Interactions of nanosilver with Escherichia coli cells in planktonic and biofilm cultures.
Tang, J., Xiong, L., Wang, S., Wang, J., Liu, L., Li, J., Yuan, F., and Xi, T. Distribution, translocation and accumulation of silver nanoparticles in rats. View abstract. Environ Toxicol.Chem. 5-1-2007;3(2):55-65. View abstract. Yen, H. J., Hsu, S. H., and Tsai, C. L. Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes. Rev Enferm 2009;32(3):173-178. View abstract. Coutts, P. and Sibbald, R. G. The effect of a silver-containing Hydrofiber dressing on superficial wound bed and bacterial balance of chronic wounds. 3rd European Conference on Advances in Wound Management; 19-22 October; Harrogate, UK. There are currently no FDA-approved over-the-counter or prescription drugs containing silver that are taken by mouth.
Sathishkumar, M., Sneha, K., Won, S. W., Cho, C. W., Kim, S., and Yun, Y. S. Cinnamon zeylanicum bark extract and powder mediated green synthesis of nano-crystalline silver particles and its bactericidal activity. Cohen LE, Spurlock R, Salem A, Mercado E. Argyria in the silver state. Gulbranson SH, Hud JA, Hansen RC. 12-18-2009;390(3):733-737. Cutis 2000;66:373-4. I. Toxicol.Lett 9-15-1998;98(3):169-179. 2008;28(2):97-99. Hyun, J. S., Lee, B. S., Ryu, H. Y., Sung, J. H., Chung, K. H., and Yu, I. J. Neurotoxicol.Teratol. Pariser, R. J. Generalized argyria. Colloids Surf.B Biointerfaces. 2010;38(12):2246-2251. In fact, the FDA deemed that all over-the-counter products that contain colloidal silver ingredients or silver salts are not generally recognized as safe or effective (1, 2). Silver deposits may also occur in your intestines, liver, kidneys, and other organs (14). The future is now: wound care in the 21st century. J Biomed.Mater.Res B Appl Biomater. View abstract. Childress, B. 2-24-2009;3(2):279-290. Kim, Y. S., Kim, J. S., Cho, H. S., Rha, D. S., Kim, J. M., Park, J. D., Choi, B. S., Lim, R., Chang, H. K., Chung, Y. H., Kwon, I. H., Jeong, J., Han, B. S., and Yu, I. J. Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats. Kemp, M. M., Kumar, A., Clement, D., Ajayan, P., Mousa, S., and Linhardt, R. J. Hyaluronan- and heparin-reduced silver nanoparticles with antimicrobial properties. Ecotoxicology. 10-15-2010;100(2):140-150. Wong, K. K., Cheung, S. O., Huang, L., Niu, J., Tao, C., Ho, C. M., Che, C. M., and Tam, P. K. Further evidence of the anti-inflammatory effects of silver nanoparticles. View abstract. Appl Microbiol.Biotechnol. Int Wound J 2010;7(4):262-270. View abstract. View abstract. View abstract. Li, W. R., Xie, X. Environ Sci Technol. Water Res 2010;44(20):6095-6103. Biochem.Biophys.Res Commun. 11-12-2009;18(20):S28, S30-S28, S36. View abstract. View abstract. Int J Nanomedicine. View abstract. Interact.Cardiovasc.Thorac.Surg 2009;8(1):153-154. Toxicol.Sci 2009;107(2):404-415. View abstract. Colloidal silver is commonly found as a dietary supplement in liquid or spray form. Jun, E. A., Lim, K. M., Kim, K., Bae, O. N., Noh, J. Y., Chung, K. H., and Chung, J. H. Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity. Ahamed, M., Posgai, R., Gorey, T. J., Nielsen, M., Hussain, S. M., and Rowe, J. J. Colloidal silver products were once available as over-the-counter drug products. Muller, G. and Kramer, A. Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity. Zhang, B., Luo, Y., and Wang, Q. Colloids Surf.B Biointerfaces. van, Hasselt P., Gashe, B. View abstract. View abstract.
Can J Ophthalmol. View abstract. J Burn Care Rehabil 1998;19(6):531-537.
5-15-2009;43(10):3933-3940. Wu, M. H. and Wu, H. Y. Silver resistance in MRSA isolated from wound and nasal sources in humans and animals. 2007; Silva, L. R., Gurgel, R. Q., Lima, D. R., and Cuevas, L. E. Current usefulness of Crede's method of preventing neonatal ophthalmia. 2010;5(4):044103. Toxicol.Sci 2010;115(2):521-534. Ophthalmology 1991;98(12):1769-1775. Selective inhibitory potential of silver nanoparticles on the harmful cyanobacterium Microcystis aeruginosa. View abstract. J Med Assoc.Thai. J Phys Chem.B 10-30-2008;112(43):13608-13619. Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos. View abstract. 2010;8:19. Small 8-17-2009;5(16):1897-1910. 11-1-2010;44(21):8337-8342. Its proponents claim that it treats various diseases, such as cancer, HIV, Lyme disease, and diabetes. J Nanobiotechnology. Wunderlich, U. and Orfanos, C. E. [Treatment of venous ulcera cruris with dry wound dressings. View abstract. Biological effects induced by nanosilver particles: in vivo study. 6-23-2009;3(6):1357-1364. 1960;63:586-591. Bong-Hyun, J, Jang-Woong, B, and Jee Yeon, K et al. You are encouraged to report negative side effects of prescription drugs to the FDA. Its present in very tiny amounts in drinking water, the food supply, and even the air you breathe (8). View abstract. Gopinath, P., Gogoi, S. K., Sanpui, P., Paul, A., Chattopadhyay, A., and Ghosh, S. S. Signaling gene cascade in silver nanoparticle induced apoptosis. Influence of hydrocolloidal silver nanoparticles on gastrointestinal microflora and morphology of enterocytes of quails. 2-25-2009;20(8):085103. Chen, X. and Schluesener, H. J. Nanosilver: a nanoproduct in medical application. View abstract. Kumari, M., Mukherjee, A., and Chandrasekaran, N. Genotoxicity of silver nanoparticles in Allium cepa. 8-15-2010;142(1-2):222-228. Hua Xi.Kou Qiang.Yi.Xue.Za Zhi. View abstract. Biotechnol.Lett 2008;30(11):1893-1899. J Biomed.Opt. Safety evaluation of silver nanoparticles: inhalation model for chronic exposure. B. Antibacterial activity and mechanism of silver nanoparticles on Escherichia coli. J Air Waste Manag.Assoc. View abstract. 3-15-2010;44(6):2163-2168. View abstract. Colloidal silvers mechanisms arent fully understood. View abstract. Biomaterials 2010;31(8):2260-2271. Gerding, R. L., Emerman, C. L., Effron, D., Lukens, T., Imbembo, A. L., and Fratianne, R. B. Outpatient management of partial-thickness burns: Biobrane versus 1% silver sulfadiazine. J Mater.Sci Mater.Med 2010;21(10):2861-2868. Romanko, M. I., Rieznichenko, L. S., Hruzina, T. H., Dybkova, S. M., Ul'berh, Z. R., Ushkalov, V. O., and Holovko, A. M. [Influence of gold and silver nanoparticles on ATPase activity of native and rehydrated cells of Escherichia coli]. View abstract. Shouse, S. S. and Whipple, G. H. I. What Is Japanese Knotweed, and Should You Try It. Environ Health Perspect. ACS Nano. View abstract. Choi, O. and Hu, Z. Numerous case studies have found that silver intake from colloidal silver dietary supplements may lead to argyria (15, 16, 17). (7). Colloidal silver might decrease how much tetracycline antibiotics the body can absorb. In fact, its considered unsafe and ineffective by the FDA. Trickler, W. J., Lantz, S. M., Murdock, R. C., Schrand, A. M., Robinson, B. L., Newport, G. D., Schlager, J. J., Oldenburg, S. J., Paule, M. G., Slikker, W., Jr., Hussain, S. M., and Ali, S. F. Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells. Silver bullet. Muhling, M., Bradford, A., Readman, J. W., Somerfield, P. J., and Handy, R. D. An investigation into the effects of silver nanoparticles on antibiotic resistance of naturally occurring bacteria in an estuarine sediment. Akhavan, O. Sudheer, Khan S., Bharath, Kumar E., Mukherjee, A., and Chandrasekaran, N. Bacterial tolerance to silver nanoparticles (SNPs): Aeromonas punctata isolated from sewage environment. 2010;84(1):63-69. 1993; Hwang, E. T., Lee, J. H., Chae, Y. J., Kim, Y. S., Kim, B. C., Sang, B. I., and Gu, M. B.
Parker, W. A. Argyria and cyanotic heart disease. 2010;5:337-342. Storm-Versloot, M. N., Vos, C. G., Ubbink, D. T., and Vermeulen, H. Topical silver for preventing wound infection. Supplement Safety. View abstract. 2010;398(2):867-876.
Morones, J. R., Elechiguerra, J. L., Camacho, A., Holt, K., Kouri, J. Int Wound J 2005;2(4):348-356. View abstract. 2010;6(2):192-197. In fact, the earliest recorded use of silver as a medical treatment dates back to the Han Dynasty in China (1500 B.C.) A Comparison of Three Silver-containing Dressings in the Treatment of Infected, Chronic Wounds. View abstract. Rev Latinoam.Microbiol. There are many Internet ads for the parts of a generator that produces colloidal silver at home. Environ Toxicol.Chem. Development of a New Polypropylene-Based Suture: Plasma Grafting, Surface Treatment, Characterization, and Biocompatibility Studies. Aquat.Toxicol. Elliott, C. The effects of silver dressings on chronic and burns wound healing. Rapid repair and regeneration of damaged rabbit sciatic nerves by tissue-engineered scaffold made from nano-silver and collagen type I. This can lead to an irreversible bluish skin discoloration that first appears in the gums. Role of sulfide and ligand strength in controlling nanosilver toxicity. Taking colloidal silver along with medications that might also harm the liver can increase the risk of liver damage. View abstract. Powers, C. M., Badireddy, A. R., Ryde, I. T., Seidler, F. J., and Slotkin, T. A. J Basic Microbiol. 6-1-2010;77(2):240-245. The effect of silver nanoparticles on phytopathogenic spores of Fusarium culmorum. Evaluation of the toxic impact of silver nanoparticles on Japanese medaka (Oryzias latipes). J Biol Inorg.Chem. View abstract. Colloidal silver proteins marketed as health supplements. Studies on interaction of colloidal Ag nanoparticles with Bovine Serum Albumin (BSA). Nanotechnology. Biotechnol.Bioeng.

View abstract. View abstract. View abstract. Silver products for medical indications: risk-benefit assessment. J Burn Care Res 2006;27(3):298-309. Tian, J., Wong, K. K., Ho, C. M., Lok, C. N., Yu, W. Y., Che, C. M., Chiu, J. F., and Tam, P. K. Topical delivery of silver nanoparticles promotes wound healing. Mohammed, Fayaz A., Balaji, K., Girilal, M., Kalaichelvan, P. T., and Venkatesan, R. Mycobased synthesis of silver nanoparticles and their incorporation into sodium alginate films for vegetable and fruit preservation. Further, no human data supports consuming colloidal silver to treat or prevent medical conditions like diabetes, cancer, HIV, digestive issues, and other illnesses (8). A. and Caldwell, D. R. Corneal argyrosis: histologic, ultrastructural and microanalytic study. Lo, S. F., Hayter, M., Chang, C. J., Hu, W. Y., and Lee, L. L. A systematic review of silver-releasing dressings in the management of infected chronic wounds. Finally, silver is found in other commercial products, such as cleaning agents, agricultural treatments, and personal hygiene products like shower gels and deodorants (7). 2007;12(4):527-534. Honey compared with 1% silver sulfadiazine cream in the treatment of superficial and partial thickness burns. The real risks of ingesting silver nanoparticles, which are present in colloidal silver products, are also unknown. Despite these concerns about safety and effectiveness, people still buy colloidal silver as a dietary supplement and use it for a wide range of ailments. Sadhasivam, S., Shanmugam, P., and Yun, K. Biosynthesis of silver nanoparticles by Streptomyces hygroscopicus and antimicrobial activity against medically important pathogenic microorganisms. J Control Release 7-14-2010;145(2):76-90. Mol.Pharm 2009;6(5):1388-1401. Am J Clin Dermatol 2010;11(1):35-44.
9-18-2009;138(3-4):325-329. 2009;5(4):452-456. Cai, Y. H. and Lu, C. S. [A clinical study of gelatamp colloidal silver gelatin sponge on preventing the complication of teeth extraction]. 10-28-2005;(40):5059-5061. Graefes Arch Clin Exp.Ophthalmol.
View abstract. Biometals 2011;24(1):135-141. View abstract. Alt, V., Bechert, T., Steinrucke, P., Wagener, M., Seidel, P., Dingeldein, E., Scheddin, D., Domann, E., and Schnettler, R. [Nanoparticulate silver. Fung MC, Weintraub M, Bowen DL. Choi, O., Yu, C. P., Esteban, Fernandez G., and Hu, Z. Interactions of nanosilver with Escherichia coli cells in planktonic and biofilm cultures.
Tang, J., Xiong, L., Wang, S., Wang, J., Liu, L., Li, J., Yuan, F., and Xi, T. Distribution, translocation and accumulation of silver nanoparticles in rats. View abstract. Environ Toxicol.Chem. 5-1-2007;3(2):55-65. View abstract. Yen, H. J., Hsu, S. H., and Tsai, C. L. Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes. Rev Enferm 2009;32(3):173-178. View abstract. Coutts, P. and Sibbald, R. G. The effect of a silver-containing Hydrofiber dressing on superficial wound bed and bacterial balance of chronic wounds. 3rd European Conference on Advances in Wound Management; 19-22 October; Harrogate, UK. There are currently no FDA-approved over-the-counter or prescription drugs containing silver that are taken by mouth.

