[19] It is a white solid. We selstuart weitzman returns

[19] It is a white solid. We sell professional do it yourself pest control (diy), exterminator and Chemically, it is a polychlorinated aromatic, classified by FRAC as a chloronitrile/phthalonitrile. Following oral administration thiol-derived metabolites were identified in urine; only 3% of the dose appeared in urine with lower proportions excreted as thiol-derived metabolites, indicating that gut microflora may play a role in the disposition andmetabolism of chlorothalonil in the rat. Was using a different plant care product for black spot on my roses (something with neem oil) that simply wasn't working. Follow label directions precisely. Some popular trade names for chlorothalonil include Bravo, Daconil 2787, Echo, Exotherm Termil, Nopcocide, Repulse, and Tuffcide.

[2], In 2019, a review of the evidence found that "a high risk to amphibians and fish was identified for all representative uses", and that chlorothalonil breakdown products may cause DNA damage. A professional dry flowable fungicide that provides preventive disease control for ornamentals and cool & warm-season grasses. Metalaxyl-M is a severe ocular irritant, but otherwise is toxicologically equivalent to metalaxyl. Peach Leaf Curl Mammalian Toxicokinetics and Toxicity of Chlorothalonil, Hayes' Handbook of Pesticide Toxicology (Third Edition), The Regulatory Evaluation of the Skin Effects of Pesticides, Safety Assessment including Current and Emerging Issues in Toxicologic Pathology, Haschek and Rousseaux's Handbook of Toxicologic Pathology (Third Edition), Pediatric Clinical Advisor (Second Edition), Biomarkers in Toxicology (Second Edition). Always read label of individual product for additional Many of the effects seen following acute exposure are consistent with irritation at the initial site of contact. This is especially true of sprays containing arsenic and malathion. Chlorothalonil is a protectant fungicide. A relatively high concentration of about 0.1% was observed in rat kidneys, one of the target organs for chlorothalonil toxicity (Parsons, 2010).

P.K. Diagram illustrating proposed metabolism of chlorothalonil following oral administration to rats. Continued administration of chlorothalonil leads to the development of a regenerative hyperplasia within the renal proximal tubular epithelium. see, Long term ratings indicate whether the active ingredient is on the. Reproduced with permission from Parsons, P.P., 2010. Statewide IPM Program, Agriculture and Natural Resources, University of California Chlorothalonil is a nontoxic halogenated benzonitrile fungicide with broad spectrum activity against vegetable, ornamental, orchard, and turf diseases. Because of its ability to disrupt microtubule assembly during cell division, benomyl causes chromosomal aberrations both in vitro and in vivo, but does not interact directly with DNA. The action on dividing cells has also raised concern for benomyl's potential teratogenicity and developmental toxicity. Sign into your account to receive your members only Savings.

Both are non-irritating and non-sensitizing for skin. Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them. An additional 0.3 is added for the ability to orient toward bell laterally, as per the decimal number recorded in parentheses. A professional fungicide for the control of turf diseases for sod farms, golf courses, athletic fields, and commercial and industrial buildings. Mammalian toxicokinetics and toxicity of chlorothalonil. The CLAMS (Clinical Linguistic and Auditory Milestone Scale) was developed, standardized, and validated for assessment of language development from birth to 36 months of age. A highly effective fungicide that targets and controls a broad spectrum of plant diseases and features a multi-site mode of action. Whether it is leaf spots or rust, Ortho has the product for you! Works great for tomato blight/early blight. Rats are especially sensitive to altered thyroid homeostasis with resultant formation of thyroid neoplasms due to their lack of thyroid-binding globulin (see Endocrine System, Chapter 58). Hepatocellular adenomas and rostral (anterior) pituitary lobe adenomas have also been reported in rodents treated with ETU, and it has caused reproductive and developmental abnormalities in rats, including major defects in fetal brain development, skeletal abnormalities, and cryptorchidism. Please try again. ", See More A professional fungicide for control of turf & ornamental diseases, including fruit & nut trees. Solves pelletbottle with demonstration (0.6), 1. According to the EPA report, "post-application exposure to HCB from chlorothalonil is not expected to be a concern based on the low level of HCB in chlorothalonil. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. For more information, Most common routes of exposure to chlorothalonil are via the skin and eyes; it may also be ingested or inhaled. (Ed. products to spray, eliminate and exterminate pests.

Toxicity: Can cause eye and skin irritation in humans, but is otherwise considered to be only slightly toxic. Use of this site is subject to certain Terms Of Use. Chlorothalonil is the third highest production volume fungicide after sulfur and copper formulations. Garden Tech Daconil Fungicide Concentrate A professional fungicide that provides long-lasting protection to crops against diseases for up to 28 days and has an excellent tank mix compatibility. This compound can be found in formulations with many other pesticide compounds. All contents copyright 2020 The Regents of the University of California.

This compound can be found in formulations with many other pesticide compounds. [14], 2,4,5-trichloro-6-hydroxyisophthalonitrile (SDS-3701), In March 2019, as a result of the previously mentioned research, the European Union banned the use of chlorothalonil[14] dated to take effect May 20, 2020. [11], The main breakdown product of chlorothalonil is hydroxy-2,5,6-trichloro-1,3-dicyanobenzene (SDS-3701). It is seen among pickers of the prickly pear cactus plant. This class of chemicals includes chlorothalonil, dicloran, HCB, quintozene, PCP, dichlorophen, dinocap, tecnazene, and chloroneb. It is applied as a dust, dry or water-soluble grains, a wettable powder, a liquid spray, a fog, and a dip. CROP PRODUCTION: 1997. It has been shown to be 30 times more acutely toxic than chlorothalonil and more persistent in the environment. ETU can be generated when produce treated with EBDC is stored or cooked, although at minute levels well below the US EPAs level of concern. Repeated administration of chlorothalonil causes hyperplasia in the forestomach of rats and mice. [2], Chlorothalonil has been detected in ambient air in Minnesota[9] and Prince Edward Island,[10] as well as in groundwater in Long Island, New York[2] and Florida. [2] Chlorothalonil-containing products are sold under the names Bravo, Echo, and Daconil. Schematic outlining potential pathways of chlorothalonil metabolism in the rat that leads to formation of toxic metabolites within the kidney. "Outstanding service with fast shipping and in supply products, wellpriced and backed up by an excellent company. Ortho Dial N Spray Hose-End Sprayer for Liquid Weed and Insect Killer, Fungicide, Fertilizer with 14 Dilution Settings. Pesticides and Air Pollution in Minnesota: The Frequency of Detection of Chlorothalonil, a Fungicide Used on Potatoes. Need Help? Solves round hole in form board reversed (0.5), 3. Avoid Ramesh C. Gupta, James W. Crissman, in Haschek and Rousseaux's Handbook of Toxicologic Pathology (Third Edition), 2013. It is noncorrosive and stable in moderately alkaline or acidic aqueous solutions. A professional broad-spectrum contact fungicide that controls more than 50 major diseases on turf and ornamental plants. Please call us at: 1-800-HOME-DEPOT (1-800-466-3337), Please enter in your email address in the following format: you@domain.com. A fungicide that controls diseases up to 14 days on vegetables, flowers, fruits and ornamental plants.

These studies indicate that excretion of thiol-derived metabolites of chlorothalonil requires glutathione conjugation and then subsequent enzymatic processing of glutathione-derived conjugates that are selectively accumulated within the kidney. Chlorothalonil is an aromatic halogen compound that appears as a grayish to colorless crystalline solid that is odorless or has a slightly pungent odor. Chlorothalonil has very low acute toxicity by the oral and dermal routes although it is very toxic by inhalation. Orients toward bell (upward directly 180) (0.5)*, 1.

It is not systemic; therefore it must be reapplied regularly during the growing season.

It inhibits fungal growth by inhibiting microtubule assembly in fungi, with minor effects in plants or mammals. The rodent oral LD50 for propiconazole ranges from 1211 to 2233mg/kg, depending on the animal species and the chemical isomer. Chlorothalonil was found to be an important factor in the decline of the honey bee population, by making the bees more vulnerable to the gut parasite Nosema ceranae. Administration of the monoglutathione conjugate to rats was shown to produce a qualitatively similar pattern of metabolite excretion to that seen following administration of chlorothalonil itself (Syngenta, 1987a,b). After three applications blight is still present. vol. It also controls mold, mildew, algae, bacteria, and fruit rots in cranberry bogs. A multi-purpose fungicide that controls leaf spots, rust, blights and more on roses, trees, shrubs and vegetables. 2. Ortho MAX Garden Disease Control Concentrate, 16-Ounce (Active Ingredient 29.6% Chlorothalonil Fungicide, Formerly Known as Daconil. FOR ALL OTHER USES or more information, read Legal Notices. The residua of various insecticides on plants may also produce dermatitis. By analogy with other chemicals that undergo extensive glutathione conjugation, it is reasonable to presume that metabolism proceeds via cysteine conjugates and N-acetyl cysteine conjugates (mercapturates) as outlined in Fig. A professional turf and ornamental fungicide and works both systemically and on contact. By continuing you agree to the use of cookies. Too much rain lately so I can't really tell. Further metabolic processing results in the formation of cysteine conjugates that may be detoxified via N-acetylase or activated to toxic thiol-derived species. Stops and prevents garden diseases. Chlorothalonil is an aromatic halogen compound that appears as a grayish to colorless crystalline solid that is odorless or has a slightly pungent odor. Sabra dermatitis is an occupational dermatitis resembling scabies. Mechanistic studies have been conducted to determine if a relationship exists between the ability to excrete urinary thiol-derived metabolites of chlorothalonil and to induce renal toxicity. [2] It is also used on golf courses and lawns (about 10%) and as a preservative additive in some paints (about 13%), resins, emulsions, and coatings. 2000-2022 Home Depot. Chlorothalonil causes irreversible and severe ocular lesions in rabbits. However, this only reduces the concentration, the substances still remain in the water. In contrast to the conclusion described in the Eawag fact-sheet, it was also possible to remove the metabolites R471811 and chlorothalonil sulfonic acid from water using a filter material based on activated carbon.

Following absorption from the GI tract, chlorothalonil is conjugated to glutathione in the liver. It has a soil half-life of approximately 2 months and is stable on exposure to ultraviolet light. For noncommercial purposes only, any Web site may link directly to this page. Rats in repeated-dose studies with metalaxyl-M developed centrilobular hepatocellular hypertrophy. Works great for tomato blight/early blight, Reviewed in the United States on June 27, 2015. Contact UC IPM, Agriculture and Natural Resources, University of California, Regents of the University of California--> We use cookies to help provide and enhance our service and tailor content and ads. Visit the Ortho Amazon Store for more products. Ortho MAX Garden Disease Control Concentrate, 16 oz. I used this product with a pump action spray container, and it worked perfectly. The Garden wouldn't be the Garden without our Members, Donors and Volunteers. No. Chlorothalonil has been labeled a Category II toxin by the EPA, which translates to "moderately toxic". Chlorothalonil is only slightly soluble in acetone, dimethyl sulfoxide, cyclohexane, and xylene. Supplies: The kit includes the following items: red ring, cup, 10 cubes, pegboard with six holes and two pegs, metal bell, crayon and paper, tissues, card with four pictures, card with six pictures, bottle and pellets, round stick, glass (made of Plexiglas), formboard with three shapes. Find answers in product info, Q&As, reviews. However, chlorothalonil was not irritating to skin when tested in a standard skin irritation study although dermal irritation has been observed in acute and subchronic toxicity studies in the rat and rabbit, indicating the potential for chlorothalonil to cause skin irritation following repeated or prolonged exposure. P. Raman, in Encyclopedia of Toxicology (Third Edition), 2014. Human relevance to these stomach and kidney tumors is discussed in a review (Wilkinson and Killeen, 1996). Inhibition of -glutamyltranspeptidase using Acivicin (Syngenta, 1985) andrenal organic anion transport using probenecid (Syngenta, 1986) decreased urinary thiol-derived metabolite excretion in rats. Can't find the product you are looking for? [5], According to the EPS, chlorothalonil is a toxicity category I eye irritant, producing severe eye irritation. Orients toward bell (1.0)* (upwardly/indirectly 90), 1. The CAT (Clinical Adaptive Test) consists of problemsolving items, for ages from birth to 36 months, adapted from standardized infant psychologic tests. It is used to protect many crops, ornamentals, and turf; and as a preservative for wood and many other materials. In addition, chlorothalonil has uses as a pesticide pest control agent, wood protectant and acaricide. [16] Switzerland followed in December 2019.[17]. Highly toxic to fish. 16 oz concentrate makes up to 64 gallons of diluted spray. This compound is a phenylamide that disrupts fungal RNA polymerase, and the R-enantiomer is much more active. A basal age is determined when all items for 2 consecutive months are scored as yes. Items for tests at the next higher age group are administered until two consecutive levels of all no responses are obtained. Chlorothalonil is classified as a general use pesticide by the US Environmental Protection Agency (EPA). Read the label to determine if the product is registered for your use. St Louis, Mosby, 2000. Mancozeb is an ethylene bisdithiocarbamate (EBDC), part of a very widely used thiocarbamate class that generates multisite fungicidal activity by complexing with and inhibiting metal-containing enzymes, including those involved with the production of ATP. Controls leaf spots, rust, blights, fruit rots, mildews, scabs, molds and other plant diseases. product for a specific pest on a specific plant to be sure it can Metalaxyl is also negative for reproductive and developmental effects, and the great majority of genotoxicity tests have been negative. Chlorothalonil is an important broad-spectrum, nonsystemic, organochlorine fungicide that has been widely used for more than 30years as an effective disease management tool for potatoes, peanuts, turf, and vegetable and fruit crops. Notes: Can cause severe eye and skin irritation. [14][15] Around the same time, research indicated chlorothalonil and other fungicides to be the strongest factor in bumblebee population decline. [3] Including nonagricultural uses, the United States Environmental Protection Agency (EPA) estimates, on average, almost 15millionlb (6.8millionkg) were used annually from 1990 to 1996. US regulations limit HCB in commercial production to 0.05% of chlorothalonil. Propiconazole is a conazole, classified by FRAC as a demethylation inhibitor. Do not apply to water or in areas where drift/runoff will cause contamination to any pond, lake or stream. Water based and for outdoor use only. It is also used on golf courses and lawns, and other agricultural crops. Mancozeb is a polymerized mixture of zinc and manganese salts of the organic molecule. Please try your search again later. It was first registered for use in the US in 1966. extermination insecticide, pesticide, chemical and bug killer treatment Despite its MOA in fungi, studies of mammalian carcinogenicity, cytogenicity, mutagenicity, teratogenicity, and reproduction were all negative. Repeated high-dose exposure of rodents causes hepatocyte hypertrophy and necrosis. Elsevier, New York, NY, pp. Even though I moved them to a new location than they have been before. Acute Toxicity of Chlorothalonil, P.P. A professional fungicide that controls diseases on professional turf-grass and ornamental plants. 19511966. black spot. This agent has antibacterial and antiviral qualities as well. In dogs, there is no evidence of either neoplastic development or the occurrence of preneoplastic lesions in the kidney or stomach. I'm using on Desert Roses (Adenium obesum) that were developing rapidly yellowing leaves, usually without black dots. If no example products are listed, [7] Technical grade chlorothalonil contains traces of dioxins and hexachlorobenzene,[2] a persistent organic pollutant banned under the Stockholm Convention. Acute Toxicity of Chlorothalonil, Michael OMalley, in Hayes' Handbook of Pesticide Toxicology (Third Edition), 2010. A broad-spectrum foliar protectant fungicide that protects crops from fungal diseases. This is done to calculate the language age equivalent and the problemsolving age equivalent. Low toxicity to birds and bees. Tumors in the upper part of the stomach and the kidney in rats and mice are believed to be due to regenerative hyperplasia, and it is assumed that a threshold can be established for carcinogenicity. Docket DF - Generic Daconil Fungicide It has also been detected in several fish kills in Prince Edward Island. From Bravo AM: Development. When ETU was fed to rats for 2 years, itproduced dose-related thyroid follicular hyperplasia at 50ppm and malignant thyroidneoplasia at 250ppm. Fung-onil Multi-purpose Fungicide Ready-to-Use Triphenyltin acetate is also used as a fungicide, while tributyltin had long been utilized as an antifouling agent, but was banned in 2008 because of its adverse ecological effects, particularly on oysters. Lawn care companies spray herbicides and fungicides throughout the spring, summer, and fall. The removal of chlorothalonil and its metabolites is usually achieved by very expensive, technically complex and unecological methods such as reverse osmosis, nano- or microfiltration. The first measurements did not even reach the detection limit. Chlorothalonil is first and foremost a broad spectrum fungicide , used to control fungi that prey on trees, vegetables, turf, small frutis, ornamentals, and other crops. Drawaperson with head plus one other part of body (1.5). : in the Group 2A of International Agency for Research on Cancer IARC are the "probable human carcinogen" substances), based on observations of cancers and tumors of the kidneys and forestomachs in laboratory animals fed diets containing chlorothalonil. Dennis vanEngelsdorp "Crop Pollination Exposes Honey Bees to Pesticides Which Alters Their Susceptibility to the Gut Pathogen. Continued regenerative hyperplasia ultimately results in progression of the kidney lesion to tubular adenoma and carcinoma. Together, this gives an ageequivalent of 4.3. Hepatic enzyme induction produced secondary effects on the thyroid, probably attributable to increased thyroid hormone catabolism. The penetration of minute, invisible thorns into the skin is the cause.Agave americana is a low-growing plant used for ornamental purposes in many southwestern U.S. communities.

At high temperatures, chlorothalonil decomposes to emit hydrochloric acid. this active ingredient may be available only for professional use. contact with eyes. Mold Ram GIT, gastrointestinal tract; GSH, glutathione. Chlorothalonil products reacts with fungi enzyme systems in a way that ultimately leads to cell death. United States Environmental Protection Agency, International Agency for Research on Cancer IARC, Reregistration Eligibility Decision for chlorothalonil, PESTICIDE USE IN U.S. Depending on species and route of administration, various glutathione conjugates can be measured as urinary metabolites (Parsons, 2001). Table 91.1. Fung-onil Multi Purpose Fungicide Concentrate. Please try again. Visually follows ring horizontally and vertically (0.5), 1. A professional fungicide that provides control fungal diseases for commercial turf-grasses, golf courses, landscape ornamentals, greenhouses and nurseries. * Free Shipping is available to the continental United States only. Figure27.12. Chlorothalonil is non-toxic to birds but highly toxic to fish. Such chemicals tend to show reactivity toward protein containing critical S electrophiles rather than toward DNA (containing critical O and N nucleophiles). Mancozeb itself has not demonstrated carcinogenicity, teratogenicity, or reproductive toxicity, although chronic studies in rats and dogs showed inconsistent small effects on thyroid morphology and depressed iodine uptake. Blight threatened our neighborhood but the the sooner you can get this on the less damage you will have. Chlorothalonil likes to bind sulfur-containing amino acids. Therefore, it reacts with fungal glutathione and disrupts numerous enzymatic cell processes. Copper sulfate, which has been used for over a century, has overall low toxicity, and remains one of the most widely used fungicides. long-sleeved shirt, and a hat that can be washed after each Staff-only pages

I wasted a lot of time trying to use that and lost all the leaves on my roses. I was very worried and it didn't look like any fungus I'd ever seen. and (Low) IV-Apply at any time with reasonable safety to bees. Roses in the Garden and Landscape: Diseases and Abiotic Disorders, Division of Agriculture and Natural Resources. I was very worried and it didn't look like any fungus I'd ever seen, Reviewed in the United States on August 20, 2016. Ortho Max Garden Disease Control Concentrate treats diseases that affect vegetables, fruits, flowers , shrubs, and ornamentals. Recent research results from a Swiss company show very good results for the removal of chlorothalonil and its metabolites. Gupta, in Biomarkers in Toxicology (Second Edition), 2019. See our Home page, or in the U.S., contact your local Cooperative Extension office for assistance. To calculate the overall star rating and percentage breakdown by star, we dont use a simple average. In addition, dilution is achieved by mixing with uncontaminated water. Testimonials . Considering that chlorothalonil has been marketed for about 30years, the reports of adverse effects are very rare. We tried various sprays and methods before buying this and nothing worked. A professional fungicide that provides effective fungal disease control on turf-grass, ornamental plants and golf courses. Both are threshold effects that are judged by the US EPA to indicate a negligible cancer risk for humans. If used on food crops, consult the product label for the appropriate harvest waiting period after applications. Plants are doing better. Responses: Responses to the test item are recorded as yes for pass and no for fail. Horizontalvertical stroke with pencil (1.5), 3. Nondiscrimination Statement. In: Krieger, R. L.G. Acknowledgements Chemical Action and Usages: Chlorothalonil is a organochlorine fungicide that is available in several different formulations and sold under the trade names of Daconil, Bravo and others. Reviewed in the United States on April 15, 2014. Two-year rodent studies showed a small increase in hepatocellular fatty change and centrilobular hypertrophy, but no increase in neoplasia. Local store prices may vary from those displayed. For example, a 6monthold child who can orient to voice, laugh out loud, and orient toward bell laterally, but who cannot ahgoo or razz has a basal age (age where child accomplishes all tasks correctly) of 4 months. Triphenyltin has moderate to high acute toxicity, but may cause reproductive toxicity and endocrine disruption. It has a molecular weight of 265.92, water solubility of 0.6mgl1 at room temperature, and a melting point of 250251C. Ortho offers a variety of products to control plant diseases. [2] To give context, the IARC evaluates Pickled vegetables (traditional Asian) as a Group 2B possible human carcinogen, and night shift work and drinking very hot beverages as Group 2A probable human carcinogen substances. The acute toxicity of chlorothalonil is summarized in Table 91.1. use. I ordered this and did the same thing, pulled all the leaves off and sprayed this weekly and NO MORE BLACK ROT! Folds paper with definite crease (1.5), 4. The rat oral LD50 is >10000mg/kg (i.e., it is practically non-toxic). A professional fungicide that controls dollar spot, brown patch, algae and others for nurseries, greenhouses, landscaping and golf courses. E-mail us and we'll get it for you!

I now spray every 3-4 weeks just in case but I haven not seen any damaged leaves since. [2], Chlorothalonil reduces and thereby deactivates glutathione. Chlorothalonil is a reactive molecule toward thio(-SH) groups. In rodent carcinogenicity studies at high doses, it has caused tumors in several organs. This stuff worked/works great. I did use it more frequently than what the directions indicated until it was gone but the plants have bounced back 100%. 2004-2022 P&M Solutions, LLC DBA DoMyOwn, Pre Emergent Herbicides (Weed Preventers), Garden Tech Daconil Fungicide Concentrate, Fung-onil Multi Purpose Fungicide Concentrate, Ferti-Lome Broad Spectrum Landscape and Garden Fungicide, Prime Source Chlorothalonil 720 Select Fungicide, Garden Tech Daconil Fungicide Ready To Use, See More However, chlorothalonil was not irritating to skin when tested in a standard skin irritation study although dermal irritation has been observed in acute and subchronic toxicity studies in the rat and rabbit, indicating the potential for chlorothalonil to cause skin irritation following repeated or prolonged exposure. All rights reserved. Trimming during landscaping can induce an irritant dermatitis caused by calcium oxalate crystals. It is practically non-toxic to vertebrates in acute tests; the rat oral LD50 is >5000mg/kg. Parsons, in Handbook of Pesticide Toxicology (Second Edition), 2001. P.P. Mode of Action Dogs dosed at 250mg/kg/day for 2 years had increased thyroid weights. A specially formulated systemic fungicide that provides effective control of plants diseases on beans, cucurbits, corn, dry bulb onion, garlic, shallot, peanut, and soybean. Blight started on my plants only 2 weeks after planting. Solves pelletbottle spontaneously (0.6), 2.

Acute toxicity is low, while chronic studies have found effects in the liver, testes, bone marrow, and gastrointestinal tract. Toxicity The rat oral LD50 is 670mg/kg for both formulations. A professional fungicide for disease control of a variety of diseases for commercial ornamental plants, conifers and turf-grass. For example, in the rodent forestomach it is an irritant, causing inflammation, hyperplasia, hyperkeratosis, and eventually papillomas and carcinomas. Fung-onil Multi-purpose Fungicide Concentrate Priya Raman, in Encyclopedia of Toxicology (Second Edition), 2005. Chlorothalonil Uses ETU is a goitrogen, which interferes with thyroid peroxidase. A professional fungicide for control of diseases on golf course greens and tees, sod farms, nurseries and commercial landscapes. Apply the product according to the directions on the label. The main product chorothalonil is what I found recommended for blight from the Purdue website. The stinging nettle is a common weed that bears tiny spines with biologically active substances such as histamine that produce itching and urticaria within minutes of contact. 0337060: Active Ingredient: 29.6% Chlorothalonil, Size: 16 oz, Type: Concentrate, Pkg Qty: 1, Package Type: Bottle. This fungicide gives broad spectrum control of vegetable, flower, fruit and ornamental diseases including but not limited to anthracnose, leaf blights, downy mildew, powdery mildew, leaf curl, scab, black spot fusarium leaf spot and many other diseases. We try to avoid using too many chemicals in our yard, but nothing was working to prevent leaf spot on a number of large photinia in our yard that act as a privacy screen. Items marked with an asterisk must be answered or demonstrated by the child and not per report of the parent/caregiver. Potential skin irritant with prolonged or repeated dermal exposure. Dryene, thiuram, carbamates, and, Encyclopedia of Toxicology (Second Edition), Encyclopedia of Toxicology (Third Edition). Several inorganic and organic metal compounds are still used as fungicides. Individual products are registered for specific uses on specific sites. Please make sure that you are posting in the form of a question. It stops and prevents diseases such as leaf spots, rust, blights, mildew, fruit rots and other plant diseases.